Atypical Cortical Patterning Leads to Poor Early LanguageExpanding upon earlier work that shows auti

Atypical Cortical Patterning Leads to Poor Early LanguageExpanding upon earlier work that shows autism begins during pregnancy, a team of researchers at UC San Diego School of Medicine, led by senior author Eric Courchesne, PhD, professor of neurosciences and director of the Autism Center of Excellence at UC San Diego, describe in the September 3, 2021 issue of Science Advances how atypical development and patterning of the brain’s surface cortex in autistic toddlers leads to poor early language outcomes. The genes involved in these effects can be traced by to mid-gestational development, and are functional important for vocal learning and human-specific evolution. “The current work indicates that individuals with poor versus good early language outcome are explained by distinct genomic mechanisms that cascade to shape cortical phenotypes and later clinical outcomes,” write the authors. — Scott LaFee -- source link

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